Stability of sunscreens containing CePO4: proposal for a new inorganic UV filter.

نویسندگان

  • Vitor C Seixas
  • Osvaldo A Serra
چکیده

Inorganic UV filters have become attractive because of their role in protecting the skin from the damage caused by continuous exposure to the sun. However, their large refractive index and high photocatalytic activity have led to the development of alternative inorganic materials such as CePO4 for application as UV filters. This compound leaves a low amount of white residue on the skin and is highly stable. The aim of this study was to evaluate the physical and chemical stability of a cosmetic formulation containing ordinary organic UV filters combined with 5% CePO4, and, to compare it with other formulations containing the same vehicle with 5% TiO2 or ZnO as inorganic materials. The rheological behavior and chemical stability of the formulations containing these different UV filters were investigated. Results showed that the formulation containing CePO4 is a promising innovative UV filter due to its low interaction with organic filters, which culminates in longer shelf life when compared with traditional formulations containing ZnO or TiO2 filters. Moreover, the recognized ability of CePO4 to leave a low amount of white residue on the skin combined with great stability, suggests that CePO4 can be used as inorganic filter in high concentrations, affording formulations with high SPF values.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Sunscreens - which and what for?

It is well established that sun exposure is the main cause for the development of skin cancer. Chronic continuous UV radiation is believed to induce malignant melanoma, whereas intermittent high-dose UV exposure contributes to the occurrence of actinic keratosis as precursor lesions of squamous cell carcinoma as well as basal cell carcinoma. Not only photocarcinogenesis but also the mechanisms ...

متن کامل

Prevention of UVA-Induced Oxidative Damage in Human Dermal Fibroblasts by New UV Filters, Assessed Using a Novel In Vitro Experimental System

BACKGROUND UVA rays present in sunlight are able to reach the dermal skin layer generating reactive oxygen species (ROS) responsible for oxidative damage, alterations in gene expression, DNA damage, leading to cell inflammation, photo-ageing/-carcinogenesis. Sunscreens contain UV filters as active ingredients that absorb/reflect/dissipate UV radiation: their efficiency depends on their spectral...

متن کامل

Production of a Novel Mineral-based Sun Lotion for Protecting the Skin from Biohazards of Electromagnetic Radiation in the UV Region

Background: Sun protection materials have been one of the major concerns in pharmaceutical industry since almost one century ago. Various materials have been found to have such an effect but there are still many unknown substances that have not been discovered.Objective: To introduce a novel mineral-based sun lotion with considerable UV absorption properties compared to commercially available s...

متن کامل

Stability Study of Sunscreens with Free and Encapsulated UV Filters Contained in Plastic Packaging

Sunscreens play a fundamental role in skin cancer prevention and in protection against photo-aging. UV filters are often photo-unstable, especially in relation to their vehicles and, being lipophilic substances, they are able to interact with plastic packaging. Finally, UV filter stability can be significantly affected by the routine use of the product at high temperatures. This work aims to st...

متن کامل

Sunscreen- The Double Edged Sword

Sunscreens have long being recognized as substances to provide effective protection against the detrimental effects of solar radiation. The deleterious effects of sun exposure can be either acute (e.g. sunburn and drug-induced photo toxicity) or chronic (potential long-term risks of repeated sun exposures like solar elastosis, keratoses, induction of skin cancers, and alteration of immune respo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Molecules

دوره 19 7  شماره 

صفحات  -

تاریخ انتشار 2014